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From Wikipedia, the free encyclopedia Fentmaxxing (sometimes spelled fentmaxing) is a term that refers to the process of maximizing one’s own ability to intake fentanyl that can be traced back to mid-2020 when it emerged on incel message boards Lookism, Sluthate, and PUAHate.[1][2] In the 2020s, the term left relatively obscure internet forums, and was popularised on TikTok.[1]